Improved procedure for production of cytochalasin E and tremorgenic mycotoxins by Aspergillus clavatus.
نویسندگان
چکیده
This report describes an improved procedure for production of cytochalasin E and tremorgens by solid substrate, agitated fermentation of Aspergillus clavatus on pearled barley.
منابع مشابه
Multitoxin analysis of <i>Aspergillus clavatus</i>-infected feed samples implicated in two outbreaks of neuromycotoxicosis in cattle in South Africa.
Aspergillus clavatus intoxication is a highly fatal neuromycotoxicosis of ruminants, especially cattle. It is caused by the ingestion of infected sprouting grain and sorghum beer residue. Locomotor disturbances, tremors and paralysis are observed. Histologically, degeneration and necrosis of larger neurons in the medulla oblongata, the midbrain, the thalamus and the ventral horns of the spinal ...
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The filamentous fungus Aspergillus clavatus is known to produce a variety of secondary metabolites (SM) such as patulin, pseurotin A, and cytochalasin E. In fungi, the production of most SM is strongly influenced by environmental factors and nutrients. Furthermore, it has been shown that the regulation of SM gene clusters is largely based on modulation of a chromatin structure. Communication be...
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عنوان ژورنال:
- Applied and environmental microbiology
دوره 31 1 شماره
صفحات -
تاریخ انتشار 1976